Thursday, 31 December 2015

HARITIAKI (HARAD)

                                                 HARITAKI
                 a)  Latin name  -  Terminalia chbula
                                 Terminalia –Proceding from the extremity
                                 Chebula -    Retz
                  b)  Family  -  Combrataceae (caffer butterfly)
                  c) Gana  - Triphala, Amalakyadi, Parushakadi, Trivruttadi,                                      Prajasthapana, Jwaraghna, Kushthaghna,                                                Arshoghna.
                 d)  Names
                             Sanskrit- Shiva, Pathya, Avyatha, Abhaya, Chetena,                          Rohini, Putana, Amrua, Jeevpriya, Pranada.
                              Hindi- Harre, Harad
                              Marathi- Hirada
                              Bengali- Haritaki
                              Gujarathi- Harad
                              Tamil-   Kandakai
                               English- Myrobalan, Chebulic myrobalan
        e) Types – 7 types
                     "विजया रोहिणी चैव पूतना चामॄताभयाम्।
                          जीवन्ती चेतकी चेति पथ्यायाः सप्त जातयः॥  "


Vijaya
Vindhta
Lambagola
Rohini
All over
Rounded
Putana
Sindhu
Small, less fleshy
Amruta
Champaranya
Fleshy
Abhaya
Champadesh
Used in netra roga and
Having 5 lines on fruit
Jivanti
Saurashtra
Yellow colour
Chetaki
Himalaya
Three lines on fruit

        f) Parts used ­-  Fruits
        g) Ayurvedic Properties –

                "कषायं दीपनं चाम्लं चक्षुष्यं चाभयाफलम्॥"    सु. सु.४६
                        "हरितकी पंचरसा अलवणा तुवरा परम्।
                         रुक्षोष्णा दीपनी मेध्या स्वादुपाका रसायनी॥
                         चक्षुष्या लघुरायुष्या बॄंहणी चानुलोमनी। "   भा. प्र.
                        Rasa – Madhur, Amla, Katu, Tikta, Kashaya
                                 Kashaya rasa prominent
                        Guna – Laghu, Ruksha.
                        Veerya – Ushna
                        Vipaka – Madhur
                        Prabhav – Tridoshahara
        g) Doshaghnata – Tridoshaghna
        h) Rogaghnata -  Netravikara, Drushtimandya, Mulvyadhi, Shoola,   Anaha, Gulma, Vibhanda, Udara, Grahani,  Shwasa,  Shukrameha, Shwetpradara, Mutrakrucch  Murtaghata, Ashmari, Jwara.
        i)  Karma – Dahashamana, Chakshushya, Rasayana, Krumighna,              Vedanasthapana, Vranashodhana, Vranaropana, Medhya,                         Balya, Dipana, Pachana, Yakruta-uttejaka.
        j) Dosage - Shodhana purpose -3 to 6 gms
                       rasayana purpose – 1 gms
                       Balaharitaki – 1 to 3 gms
        k) kalpas – Abhayadi Modaka, Abhayarishta, Pathyadi vati,     Pathyadi kadha, Vyaghriharitaki, Agastiharitaki, Gandharvaharitaki,                           Haridra khanda.
        l) Strotogamitwa -  Rasavaha, Majjavaha, Raktavaha, Medovaha.
        m) Chemical composition-
           Phenolic acid, terpenoids, tannins, luminol-which is an                            antioxidant, vaniline, l-ascorbic acid, poly-l lycine                     hydrobromide,cupric sulphate, analogs of vitamin E,                              vitamin E- fat soluble antioxidant, Vitamin E- water soluble               antioxidant, l- glutamine which prevent cataract, gallic acid.                 
·         luminol-which is an antioxidant.
·         lycine, glutamine and vaniline are essential amino acids.
·         Gallic acid acts as hypoglycemic, hypolipidemic, anti-fungal, antioxidant. It is helpful in albuminourea and showed regeneration of beta cells of pancreas. Gallic acid restores total protein, albumin, and total body mass of diabetic patient to near normal.
                                           


Wednesday, 30 December 2015


B.AYURVEDIC REVIEW

NETRA SHARIRA
Vedic literature has explained the anatomy of eye and its various associated parts. Brihadaranyak Upanishad is the most ancient vedic literature that narrates the two akshi, one as the Vishwamitra and the other as the Jamadagni.
Acharya Sushruta has given much more importance to the most precious organ ‘Eye (Netra)’ in Shalakya part and explained eye anatomy scientifically. Eye is one of the five sense organs and is a Matruja Avayava.

Synonyms:-
Netra, Nayana, Chakshu, Akshi, Netra Golaka, Nayanabudbuda, Akshi Golaka , Drishti etc.

Constitution of Eye: -
Eye is made up of all the five elements of which the universe is built. Our body is also known as Panchbhautika and the same way each and every organ has peculiar combination of Panchmahabhuta. Acharya ushruta has clearly mentioned the contribution of Panchmahabhuta for Indriya as follows:-
   "पलं भुवो अग्नितो रक्तं वातात् कृष्णं सितं जलात्।
    आकशादश्रुमार्गाश्च जायन्ते नेत्रबुद्बुदे॥"
सु. . /११







NETRA RACHANA SHARIR


Shape:
Acharya Sushrutha had explained two terms for Eye viz. Nayana and Netra in uttara tantra 1st chapter. Nayana and Netra suggest shape. Nayana, which suggests the external appearance of the eye in the orbit, means the Eye is like a bubble floating over water i.e. round in shape and soft in consistency and Netra means the Eyeball almost round in shape and resembles the cow’s teat.
Dimensions:
 "द्वयांगुलबहुल्यं स्वान्गुष्टोदरसंमितम्।
  द्वयांगुलं सर्वतः सार्धं भिषंनयनबुद्बुदम्॥
 सुवृत्तं गोस्तनाकारं सर्वभूतगुणोद्भवम्।"
                                                सु../,१०


Anguli Pramana term has been suggested the unit of measure in context to the measurement of Eye by Acharya Sushrutha. It is equal to swangusthodara which has been clearly mentioned by the commentator Dalhana that the dimension of this one anguli is equal to the central part of the thumb of an individual.
Circumference:
It is stated that, the thickness or antero-posterior diameter of an eyeball is two anguli and the circumference i.e. horizontal and vertical diameter two and a half angulas. The distance between two Eyes is two angulas.
Morphology of Eye:
As mentioned above, eye is almost round in shape and also resembles the teat of the cow. It is two fingers broad, a thumb’s width and two and a half fingers in circumference. The distance between the two eyes is two finger breadths.
In this context (i.e. reference to the description of Eye), Acharya Sushruta has mentioned the following important structures as:
"मंडलानि संधींश्च पटलानि लोचने।
यथाक्रमं विजानीयात् पन्च षट् षडेव च॥"
                                            सु. . /१४
1)   Akshi andhana
2)   Peshi and snayu
3)   Marma
4)   Sira and Dhamani
5)   Six Patala
6)   Six Sandhi
7)   Five Mandala


1. Akshi Bandhana:
The most responsible factors for proper alignment of eye are The Siras, Kandaras, Meda, Kalakasthi and Shleshma. Especially Shleshma, along with siras takes part in the bandhana karma of the eyeballs. Here, Dalhana opines that Sira in the reference includes both the Sira and dhamani, and kandara is meant for Snayu (muscle) and peshi.
"सिराणां कन्डराणां मेदसः कालकस्य च।
गुणाः कालात् परः श्लेष्मा बन्धने अक्ष्णोः सिरायु्तः॥"
                                सु.. /१९
2. Peshi and Snayu:
"द्वे नेत्रयोः।"
           सु. शा. /३७
The Peshis in the eyes are Mandala in shape and are two in number, whereas, the Snayus are of pruthu type and 30 in number.
3. Marma:
Marma are vital points of the body and disturbance to which may result in various complications. Mainly two Marmas, Apanga and Avarta, are related to Eye. Apanga marma is situated on outer side of the orbits below the lateral end of the eyebrows, ½ angulas in size and is a Sira Marma. Avarta Marma is situated above the lateral end of eyebrow, of same size and Sandhi type of Marma. Any injury to these sites may result in blindness and diminished vision.
4. Sira and Dhamani:
"अष्टौ नेत्रयोः वातवाहिनीनां सिराणां व्याख्यातं भवति्।
एष एव विभागः शेषाणामपि।  विशेषतस्तु पित्तवहिन्यो नेत्रयोर्दश॥"
                                                                    सु. शा./
As per Acharya Sushrutha, 38 Siras are found in the Eye which transport Vata (10), Pitta (10), Kapha (10) and Raktha (8). While, Acharya Vagbhata demonstrated that 65 Siras are present in the Eye but details of the 65 Siras are not available.
"ऊर्ध्वगाः ......रुप....द्वाभ्यां,..द्वे अश्रुवाहिन्यौ,....||"
                                                             सु. शा./                 
Among 4 Dhamani, 2 are meant for Roopavahana and rest two is for drainage of ashru to the Eye.
5. Asthi and sandhi:
Arunadatta, in his commentary opines that Tarunasthi is present in Akshikosha (Lids).

SANDHI:
The junction region between two Mandala (in relation to the Eye) is considered as Sandhi of the related Mandala which are classified as follows;
"पक्ष्मवर्त्मगतःसन्धिर्वर्त्मशुक्लगतोअपरः
शुक्लकृष्णगतस्त्वन्यःकृष्णदृष्टिगतोअपरः॥
ततःकनीनकगतः षष्ठश्चापांगः स्मॄतः।"
                                          सु. . /१६
1.  Pakshma Vartmagata Sandhi
2.  Vartma Shuklagata Sandhi
3.  Shukla Krishnagata Sandhi.
4.  Krishna Drushtigata Sandhi
5.  Apanga Sandhi
6.  Kaneenika Sandhi


1)   Pakshma Vartmagata Sandhi:
The juncture line of Pakshma and Vartma (i.e. the lid margins) where cilia grow are termed as Pakshma Vartmagata Sandhi. Acharya Sushruta has stated that the disease Krimigranthi of the Sandhi occurs in this Sandhi particularly.
2)   Vartma Shuklagata Sandhi:
It means the juntion region of Vartma and Shukla mandala where the disease Parvani occurs.
3)   Shukla krishnagata Sandhi:
The circular joining line in between Shukla and Krishna Mandala is Shukla Krishnagata Sandhi. One of the 8 pathogenesis namely Alaji occurs in this particular Sandhi.
4)   Krishna Drushtigata Sandhi:
This Sandhi is the junction line in between the Krishna Mandala and Drushtimandala.
5) Kaneenika Sandhi:
Acharya Sushruta has only mentioned the term “Kaneenika Sandhi”. He has not given any explanation with respect to this type of Sandhi, Whereas Acharya Dalhana has clarified by the words “Kaneenikagato nasa sameepavasthitah”. All the Acharyas mention details regarding the affections of Sandhi. It is stated that Puyalasa and 4 types of Shrava are the affections of this particular Sandhi.
6) Apaanga Sandhi:
Acharya Dalhana has defined this Sandhi as “Bhru pucchanthatah sthithaha” i. e. near the Brhu Puchcha or towards the temporal region. Three Sandhi termed as ‘Vartma Shuklagata’, ‘Kaneenika’ and ‘Apaanga’ are supported by Sandhi Bandhana. The clinical entity Vatahata Vartma (Ptosis) also occurs here, when it is vitiated by the aggravated Vata.
PATALA:
The term Patala means a veil, which denotes a thin membrane or skin or a layer. Acharya Dalhana says that it is having the thickness of 1/5th Drushti. Six Patala or layers are declared to be present in the eye. The 4 Patala have been associated in eye proper and 2 Patala are situated outside the eye i.e. Urdhwa Vartma Patala (Upper lid) and AdhoVartma Patala(lower lid). The disease Adhimantha occurs in all the above structures, hence the name “Sarvakshi roga.
Tejojalashrita patala:

This is the outer most among the 4 patala. Acharya Dalhana denotes teja as “Alochaka Teja Sanshraya Siragata Rakta” i.e. the Alochaka Pitta which is responsible for vision and is present in the blood vessels and Jala as Twakgata Rasadhathu. Acharya Indu has defined the word Ashraya as “Apyayitha” means thereby ‘to nourish’. Hence, Tejojalashrita Patala is supported or nourished by Rasa and Rakta Dhathu of the body.

Mamsashrita patala (Pishita-ashrita patala):
This is the second Patala, nourished and supported by Mamsa Dhathu.

Medashrita patala:
Medodhathu nourishes this 3rd Patala.

Asthyashrita patala:
Asthi Dhathu of the body supports the innermost or 4th Patala in general and by the Kalakasthi in particular. Asthyashrit means which remains attached with asthi or gets nourishment from asthi. Majja dhatu remains attached with asthi, that is asthyashrit. So this patala is nothing but the majjagat patala for treatment and pathology point of view. Majja nourishes the 4TH patala. For the convenience majja can be compared with nervous tissue of the eye that is retina. As far as the eyeball is concerned, there is no direct relation with asthi dhatu but it can be a nervous coat of the eye where all the retinal pathologies or disorders observed.
MANDALA:
Mandala term is used for the consecutive circular areas of the eye, which are as follows

  1. Pakshma mandala
  2. Vartma Mandala
  3. Shweta mandala
  4. Krishna Mandala
  5. Drushti Mandala

The Mandalas are arranged successively from outside to inside:

Pakshma Mandala
Pakshma or cilia of the eyelids form the outer most Mandala of the eye or eye lashes

Vartma Mandala
Vartma Mandala means the circle formed by the conjunction of upper and lower eyelids of eye ball. Two Nimeshini siras, situated in eyelids perform the function of Nimesha and Unmesha (blinking). According to Acharya sushruta eyelids are the seat of 21 diseases and Acharya Vagbhata explain 24


Shweta Mandala-
The whitish part, inner to eyelid and beyond the black circle is known as Shweta Mandala, when both the lids are open. Sushruta has encountered 11 pathogenesis in shweta Mandala and 13 according to Vagbhata.

Krishna Mandala-
Krishna Mandala is the anterior most circle of the eye, blackish in colour and 1/3rd size of the whole eye as per Sushruta. A term TARAKA for one of the structures of the Eye is also used by Sushruta, which is having the same size. The Drushti Mandala is enclosed in this Mandala. Sushruta has mentioned four clinical entities in this Mandala, whereas, they are five in view of Acharya Vagbhata.

Drushti Mandala-
Drushti Mandala is the last and innermost circular structure of the Eye. According to the statement of Dalhana, Videha opines that the diameter of Drushti Mandala is equal to 1/7th of the Krishna Mandala.

"कॄष्णात् सप्तमिच्छन्ति दॄष्टिं दॄष्टिविशारदाः।"
                                                     सु../१३

 Acharya Sushruta also agreed with the statement of Dalhana. Again it is said to be equal to 1/9th part of the TARAKA.
              " मसुरदलमत्रां तु पंचभूतप्रसादजाम्।
               खद्योतविस्फुल्लिंगाभामिद्धां तेजोभिरव्ययैः॥
               अवॄत्तां पटलेनाक्ष्णोर्बाह्येन विवराकॄतिम्।
               शीतसात्म्यां नॄणां दॄष्टिमाहुर्नयनचिन्तकाः॥" सु. सु.
Sushruta stated the structure of Drushti in above shloka.
-Dimensions-  Masurdalamatra means equal to cotylidon of masura.
-Panchbhautikatwa- Drushti is made up of five vital tatwas as                                 pruthvi, jal, tej vayu, aakash.
-khadyotvisphullingabha- Drushti spark like a lightening creature.
-Tejobhi- Like particles of light.
-Avyay- Which does not have end or metabolism.
               "अव्ययै: उपचयापचयरहितैस्तेजोभिर्विशिष्टा।"
                                                          डल्हण
-Avruttam patelanakshno- It is covered with various coverings                               (patalas) of netras.
-Vivarakrvtim- It looks like a small circular hole.
-Shitsatmya- Shit ahar and vihar is benefecial for drushti.
CLASSIFICATION OF EYE DISEASES
Shalakya Tantra consists of diseases of eye, ear, nose, throat, Head, oral cavity. In general the diseases of eye occupy the important position in Shalakya Tantra. The detailed description of the eye diseases have been elaborated in Sushruta samhita and Ashtang Hriday. The enumeration of eye diseases according to various authors is as follows:-

SS
AS
AH
MN
YR
BP
Sa
Vartmagata rogas
21
24
24
21
21
21
24
Sandhigata rogas
09
09
09
09
09
09
09
Shuklagata rogas
11
13
13
11
11
11
13
Krishnagata rogas
04
05
05
04
04
04
05
Drishtigata rogas
12
27
27
12
12
12
08
Sarvagata rogas
17
16
16
17
17
17
08
Others
02
-
-
02
17
17
08
Total
76
94
94
78
78
94
100
SS- Sushruta samhita,                               AS- Ashtanga sangraha,
AH- Ashatnga Hridhaya,                            MN- Madhav nidana,
YR- Yoga ratnakara,                                  BP- Bhava prakasha,         
  Sa-Sharangdhara
Nidana:
Nidana plays a vital role in the progression of the disease. The exact
goal of the treatment is achieved by avoiding the Nidana of the diseases is very important. A person though takes completetreatment without avoiding the Nidanas it’s merely useless. Tritiya Chaturtha Patalgat dosh drushti occurs due to vitiation of doshas due to hetu sevana. These are same as hetus of samanya netra rogas.
 Various etiological factors can be studied under differently as listed
in the following table.

उष्णाभितप्तस्य जलप्रवेशात् दुरेक्षणात् स्वप्नविपर्ययाच्च।
प्रसक्तसंरोदन कोप शोक क्लेशाभिघातादतिमैथुनाच्च॥
शुक्तारनालाम्ल कुलत्थमाष निषेवणाद्वेगविनिग्रहाच्च।
स्वेदादयो धूमनिषेवणाच्च छर्देविघातात् वमनातियोगात्॥
बाष्पग्रहात् सुक्ष्मनिरिक्षणाच्च नेत्रे विकारान् जनयन्ति दोषाः।"
                                                                         सु. . /२६,२७
Poorvaroopa :
" तत्राविलं ससंरम्भमश्रुकंडुपदेहवत्। गुरुषातोदरागाद्यैर्जुष्टं चाव्यक्तलक्ष्णैः॥
सशूलं वर्त्मकोषेषु शूकपूर्णाभमेव च। विहन्यमानं रुपे वा क्रियास्वाक्षि यथा पुरा॥"
                                                              सु. . /२१,२२,२३


·          Avila : Dirty eyes with discharge
·          Sa sarambhashru : Angry look with congestion and watering of eyes.
·          Kandu : Itching sensation
·          Upadeha : Sticking of eyelids due to organized discharge
·          Guru : heaviness of lids
·          Ushna : Burning sensation
·          Toda : Pricking pain
·          Raga : hyperaemia
·          Shooka Poornabham : foreign body sensation
·          Vihanyamanam roopam : Visual disturbance.
·          Kriyaahani : Difficulty in opening and closing the lids and
        Improper visualization.
 Samprapti of Eye disease
सिरानुसारिभिः दोषैः विगुणैरुर्ध्वमागतैः।
जायन्ते नेत्रभागेषु रोगाः परमदारुणः||
                                                सु.उ.१/२०,२१
         From the onset of Dosha Dushya Dushti till the evolution of the Vyadhi there occurs various Vikruti. Samprapti explains such series of pathological stages involved. It tells us about the total pathogenesis of a disease.         According to Sushruta, the vitiated Dosha spreads to Jatru Urdhva Bhaga through the Sira and leads to eye diseases. 
Samanya Samprapti of Netra Roga:
         The Samanya Samprapti of Netra Roga that is explained in classics can be considered as the base to understand the Samprapti of eye disease
सर्वरोगनिदानोक्तैरहितै: कुपिता मला:
अचक्षुष्यैर्विशेषेण प्राय: पित्तानुसारिण:
सिराभिरुर्ध्व प्रसॄता नेत्रावयवमाश्रिता:
वर्त्मसन्धि सितं कॄष्ण दृष्टिं वा सर्वमाक्षिवा
                                             .सं .११-
         Aacharya Vagbhata in Ashtanga Hridaya and Ashtanga Sangraha has not explained specific nidana for Netra Roga, but quotes that, the Achkshushya Nidana mentioned in Sarva Roga Nidana Adhyaya of Nidana Sthana lead to aggravation of respective Dosha and spread to Urdhva Jatru Bhaga through Pittavaha Sira and manifests Akshi Roga.

General principles of treatment :-
तत्र सम्भवमासाद्य यथादोषं भिषगजितम्
विद्ध्यान्नेत्रजारोगा बलवन्त: स्युरन्यथा
                                              सु../      
          After watching all the prodromal features of eye diseases, a prophylactic treatment should be given according to the affection of doshas.                        
संक्षेपत: क्रियायोगो निदानपरिवर्जनम्
वातादिनां प्रतीघात: प्रोक्तो विस्तरश: पुन:
                                               सु../२५
           Hetu is a soul of diseases, without hetu the process of samprati (pathology) cannot be completed. Therefore Aacharya sushruta said that if you control the hetu the further process of any diseases can be checked out ,precisely speaking Nidana is the root cause of the disease process and removal of that cause is the best treatment i.e management essentially consists of avoidance of the etiological factors and specifically in detail it implies counteracting the increased doshas.
           As every eye disease starts from the increase of the doshas, and their abnormal accumulation in the eye the first & most important step is to throw vitiated doshas out of the body by     proper management.
CONCEPT OF TIMIRA                 
              Sushrutacharya has described the symptoms of Timir according                  to four patalas and according to dosha  6 types as  vataja,  pittaja,  kaphaja,  raktaja,  sannipataja and  parimlayi.  
Definition of Drishti   
                  
मसूरदलमात्रां तु पन्चभूतप्रसादजाम्
खद्योतविस्फ़ुलिन्गाभामिद्धां तेजोभिरव्ययै :
आवॄत्तां पटलेनाक्ष्णोर्बाह्येन विवराकॄतिम्
शीतसात्म्यां नॄणां दॄष्टिमाहुर्नयनचिन्तका :
                                                   सु .. /
         The ancient ophthalmologists well versed in the anatomy of eye provoked that the drishti  of the eye is the quintessance of the five material elements with that of the eternal light predominating there in this principle of light neither increasing nor decreasing in this case. It is naturally accustomed to cold from the very nature of its temperament and covered by the outer coating of the organ proper.
                                                                                               
        It looks like a hole and is equal in dimension to that of a masura seed.



                     mÉÇcÉ pÉÑiÉÉÎlqÉMüÉ Sìè¹Ï: qÉxÉÑUÉkÉïSsÉÉåÎlqÉiÉÉ ||                                      
                                                                                                                    (M.N.madhukosh.59/29)
   But acccording to Nimi,quoted in Madhava’s commentry by shrikantha,the  dimention of the drishti is equal to only a half of that of a masura pulse.
Diseases of Drishti 
                     
                     UÉaÉÉxiÉSÉ´ÉrÉÉlÉç bÉÉåUÉlÉç wÉOû cÉ wÉOèû cÉ mÉëcɤqÉWåû |
                       mÉOûsÉÉlÉÑmÉëÌuɹxrÉ ÌiÉÍqÉUxrÉ cÉ sɤÉhÉqÉç ||
                                                          सु../                                  
           Sushrutacharya has described twelve kinds of diseases peculiar to region of Drishti and also the features of the disease “Timira” (loss of vision) which affect the patalas. Symptoms of  the four patalas when the deranged doshas affecting them  as follows-
 Patal:
The word patal is made up of dhatu Pat means veshthane i.e. to cover.Acharya Sushrut has described six patals out of which two patals are located outside the eyeball namely Vartma patals.Remaining four are situated inside the eyeball, which are Tejojalashrit, Pishitashrit, Medashrit and Asthyashrit. All these patals can be correlated with various parts of eyeball described in conventional medicine.
Correlation of Patals with different parts of eyeball:
 Vartma Mandals are two in numbers. Vartma Mandals mentioned in ayurved can be correlated with Eyelashes and eyelids. First outer layer is also called tejojalashrit and having almost same features as Cornea and Sclera. There is almost similarity between Mansashrit Patal mentioned in Ayurved and Coroid and Vitreous humour described in Morden science.Third Patal i.e. Medashrit Patal can be compared with lens and retina.Forth Patal,which is Asthyashrit Patal, is almost same as Retina, Macula and Optic disc.
Symptoms: When the first patala affected                                       
सिराभिरभिसंप्राप्य विगुणो अभ्यन्तरे भॄशम्    प्रथमे पटले दोषो यस्य दॄष्टौ urÉuÉÎxjÉiÉÈ
अव्यक्तानि रुपाणि सर्वाण्येव प्रपश्यति      सु../                  
   Sushrutacharya has described that when the deranged doshas  passing through the siras of the eye & get affected to the first patal of netra . Symptoms are developed like all external objects appear dim and hazy to the sight.
       सिरानुसारिणि मले प्रथमं पटलं श्रिते। अव्यक्तमीक्षते रुपं व्यक्तमप्यनिमित्तत:         वा..१२/
While vagbhatacharya has enumerated that, malas travelling through the siras when get localised in the first patala then the person does not see things which are clearly manifested.                                                                                                                                       Symptoms: When the second patala get affected -                          
                           SìÓ¹ÏpÉëÑzÉÇ ÌuÉuWûsÉÌiÉ Ì²iÉÏrÉÇ mÉOûsÉÇ aÉiÉå |
                            qÉͤÉMüÉqÉzÉÇMüɶÉÉÌmÉ eÉÉsÉMüÉÌlÉcÉç mÉzrÉÌiÉ ||
                           qÉÇQûsÉÉÌlÉ mÉiÉÉMüÉ¶É qÉËUcÉÉÌlÉ MÑÇüQûsÉÉÌlÉ cÉ |
                           mÉËUmsÉuÉÉÇ¶É ÌuÉÌuÉkÉÉiÉ uÉwÉïÇqÉpÉëÇ iÉqÉÉÇÍxÉ cÉ ||
                           SÕUxjÉÉÌlÉ cÉ ÂmÉÉÍhÉ qÉlrÉiÉå cÉ xÉÍqÉmÉiÉÈ |
                           xÉqÉÏmÉxrÉÉÌlÉ SÕUåcÉ Sìè¹åaÉÉåcÉU ÌuÉpÉëqÉÉiÉç ||
                           rɦÉuÉÉiÉÌmÉ cÉÉirÉjÉï xÉÔÍcÉmÉÉzÉÇ lÉ mÉzÉ
                                                              (Suut..7/7-1O)

     Sushrutcharya has narrated that false image of flies, hairs, or cob-webs, rings (circular patches) flags, ear rings appear- to the slight external objects seem to be enveloped in mist or haze or as viewed rain on cloudy days and meteors of different colours, seem to be falling constantly in all directions in the event of deranged Doshas being similarly confined in the second patala of the Drishti.
          In such cases,the near appearance of an actually remote and the contrary also should be described to some deficiency in the range of vision which in capacitates the patient from looking through the eye and hence from threading needle.

  
Symptoms: When the third patala get affected by the  doshas are as follows :-
 ऊर्ध्वं पश्यति नाधस्तात्तृतीयं पटलं गते
महान्त्यपि रुपाणि च्छादितानीव वाससा
कर्णनासाक्षियुक्तानि विपरीतानि वीक्षते
यथादोषं रज्येत दॄष्टिर्दोषे बलीयसि
अध:स्थिते समीपस्थं दूरस्थं चोपरिस्थिते
पार्श्वस्थिते तथा दोषे पार्श्वस्थानि पश्यति
समन्तत: स्थिते दोषे संकुलानीव पश्यति
दृष्टिमध्यगते दोषे एकं मन्यते द्विधा
द्विधास्थिते त्रिधा पश्येत् बहुधा चानवस्थिते
तिमिराख्य: वै दोष....
                                               सु../११-१५

तिमिराख्य: तिमिर रागप्राप्तस्य तिमिरस्य काच इति
                                                               डल्हण
प्राप्नोति काचतां दोषे तृतीयपटलाश्रिते
तेनोर्ध्वमीक्षते नाधस्तनुचैलावृतोपमम्
यथावर्णं रज्येत दॄष्टिर्ह्रीयेत क्रमात्          वा..१२/
Sushrutacharya has described that when the deranged doshas get infiltrated into third patala,objects situated high above are seen and those below remain unobserved. The Doshas affecting the Drishti,if highly enlarged,impair their specific colours to the objects and even large objects seem to be covered with a piece of cloth. The images at objects and persons with eyes and ears etc, seem to be otherwise. The deranged doshas are situated at and obstructing the lower, upper and lateral parts of the drishti respectively shut out the view of near,distant and laterally                 objects.
       A dim & confused view of the external world is all that can be had when the  doshas spread over and affect the whole of the drishti. A thing appears to the sight as if cut into two when the  Doshas affect middle part of the drishti and as triply divided when the doshas are scatttered in two parts,while a multi  image of the same object is the result of the manifold distributions of movalbility of the doshas over the drishti.
Symptoms: when fourth patal affected:
 तिमिराख्य: वै दोष: चतुर्थं पटलं गत:
रुणध्दि सर्वतो दृष्टिं लिंगनाश: उच्यते
iÉÎxqÉllÉÌmÉ iÉqÉÉåpÉÑiÉå lÉÌiÉÂRåû qÉWûÉaÉSå||
cÉlSìÉÌSirÉÉæ xÉlɤɧÉÉuÉliÉUϤÉå cÉ ÌuɱÑiÉ:
ÌlÉqÉïsÉÉÌlÉ cÉ iÉåeÉÉÇÍxÉ pÉëÉÎeÉwhÉÔÌlÉ cÉ mÉzrÉÌiÉ|ç
एव लिंगनाशस्तु नीलिकाकाचसंजित:
                                                सु../१६-१८
लिंगं चक्षुरिन्द्रियशक्ति:,तस्य नाशो यस्मिन् लिंगनाशो दोष:
                                                     डल्हण
तत्राप्युपेक्षमाणस्य चतुर्थं पटलं गत:
लिंगनाशं मल: कुर्वन् च्छादयेद् दॄष्टिमंडलम्
                                                    वा..१२/
                           mÉëÉmlÉÉåÌiÉ MüÉcÉiÉÉÇ SÉåwÉå §ÉÑÌiÉrÉ mÉOûsÉÉÍ´ÉiÉå ||
                           iÉjÉÉmrÉÑmÉå¤ÉqÉÉhÉxrÉ cÉiÉÑjÉï mÉOûsÉÇ aÉiÉÈ ||
                           ÍsÉ…lÉÉzÉÈ qÉiÉÈ |
                                                                 (As.San.ut.C.15/7-8)
                           LMü LuÉÉÅxÉÉæ mÉËUqÉsÉÉÌrÉ UÉåaÉÉåÅUÉaÉmÉëÉmiÉ: ||
                           xÉlÉç ÌiÉÍqÉUÉZrÉ È UÉaÉmÉëÉmiÉxiÉÑ MüÉcÉMüÉZrÉ |
                           xÉ LuÉ ÌMügÍcɬzÉïlÉ lÉÉzÉMüÉUÏ ÍsÉ…lÉÉzÉÈ ||
                                                    (Su.Ut.DalhanComm.C.7/25)

      Both of them have mentioned the harmful diseases kacha and
lingnasha in the next patalas.  
     

Symptoms of different types of timira according to Sushruta & vagbhat
Sushruta (ut .c.7/19/25)
Vagbhat(ut.c.15/9,13,16,20,21)
Vataja timira
External objects are viewed as cloudy  moving crooked and red coloured
Things are seen as though covered unsteady ,dirty light red and sometimes clear,sees network /web of hairs mosquitoes ,rays of light etc
                                           Pittaja timira
Things appear to be invested with the different colours of the spectrum of the rainbow of the glow worm of the flash of lightening or of the features of the peacock or with a dark blue tent bordering on black.
Person sees lightening fire,fly bright/shining things, colours like the features of the peacock and partridge generally blue in colour.
Kaphaja timira                  
A thick white coat like that of a pack of white clouds or deep white chamara seems to intervene in everything which look white and oily and dull and appear hazy and cloudy in a fine day or as if laid under a sheet of water
Person usually sees things as moist white resembling the sankha indu (moon kundakusuma )&kumuda



 STUDY OF PRAMEHA
 Prameha means watering and is derived from the root ‘miha sechane’. In the reference to disease of human beings, it may have a meaning of passing urine, qualified by prefix ‘Pra’ meaning excess in both frequency and quality. Prameha is also described as ‘Prabhuta-mutrata’ and Avil Mutrata (excessive urination with increased turbidity of urine).
          The etiology, pathogenesis and management of prameha mentioned in ayurvedic classics resembles with Diabetes mellitus. Prameha is characterized by urinary disturbances and based on Dosha predominance, it has been differentiated in 3 types which again sub classified into twenty types. There are classified in the basis of color and physical characteristics or urine. These different types of Prameha can also be correlated with systemic urological and nephrological conditions.
The mankind very well aware of Prameha since antiquity and it holds great importance among the diseases because it is a frequently occurring disease and originated from Havish, a special food which normaly serves at the time of Yajnya, organized by Dakshaprajapati. Etiology, symptomatology, treatment and complications of Prameha are described in details in all major Samhitas.
The term ‘Astharva’ mentioned in Atharvaveda 1/2/4 can be coined to Prameha. For maintaining positive and good health, Puranas and Smrutis also focus on Ayurveda and Prameha. Treatment of Kshudra and Akshudrameha has been described in Agnipauran (Agnipuran 283/15). Garud puran has mentioned vyadhi with its complication and treatment (Garud Puran 159).
Samhita Granthas has contributed majorly in dealing Prameha disease. In Charak Samhita, Prameha is described in Sutra Sthan, Nidan Sthan as well as in Chikitsa Sthan. Etiological factors, signs and symptoms, pathogenesis/Samprapti, Upashya are described in Nidan Sthan (4th chapter). In 6th chapter of Chikitsa Sthan, Acarya Charak explain treatment part, the line of treatment, prognosis, various combinations and formulation to be used in the management of Prameha. Acharya Charak also describes pathogenesis and Prameha Pidaka in Kiyantashirshiya Adhayay (Sutra Sthan 17).
Acharya Sushrut described in Nidan Sthan and in Chikitsa Sthan in three different chapters; 1) Prameha Chikitsa, Madhumeha Chikitsa and Prameha Pidaka Chikitsa. Prameha described after Kustha Vyadhi. Gayadas explained in hiscommentary Nyayachandrika that Tridosharabhatva (predominance of all three Doshas in pathogenesis of the disease), Mahavyadhitva (difficult to treat and cure) and Asadhyatva (Incurable), are common factors in Kustha and Prameha (Su. Nidan 6/1 Gayadas)
In both Asthangsangraha and Asthanghridaya, Prameha has been included in Asthangsangraha. Both granthas describe Prameha after ‘Ashmari’. The classification of Prameha has been done on the basis of involvement of Doshas (i.e. Vataj, Pittaj and Kaphaj). Madhavkar has mentioned Prameha and Prameha Pidaka after Ashmari in Madhav Nidan.
PRAMEHA SAMANYA NIDANA:-
Acharyas Charak, Vagbhat and Sushruta have classified the Prameha Nidan into Aahar, Vihar and Manas factors.
1.   Apathyakar Ahar
It includes use of new grains like Hayanak, Yavak, Cinaka etc. Use of new peas, black gram and other pulses along with ghee, tila, tilapaste and the use of sugarcaine juice. Frequent use of milk, heavy unctuous food and food having sour and saline taste, rice from newly harvested crop and fresh wine. All the materials increasing Kapha have been said to cause Prameha in susceptible individuals.
  1. Apathyakar Vihar
  2. It includes excessive sleep, sedentary habits and lack of physical and mental exercises and lack of elimination therapies. These causative factors increase Kapha.
  3. Manas
Manas causes include exposure to worry grief, anger and anxiety.

VISHESH NIDANA:-
There can be categorized three types of Vishesha Nidan
1.   Kaphaj Prameha Nidan
Frequent and excessive use of new cerels like Hayanak, Yavaka, Cinaka, Uddailaka, Naisadha, Utkata, Mukumdaka, Mahavrithi, Pramodak. Use of new legumes like Harenu and black gram, meat domesticated, marshy and aquatic animals, vegetables, sesum paste. Use of various preparations of flour, Payasa, Krushara, Vilepi and sugar cane products, milk and new wines. Lack of physical exercise, excessive sleep I day and night, prolong sitting and also other similar regimens producing Kapha and Meda are the specific etiological factors for Kaphaj Prameha
2.   Pittaj Prameha Nidan
Those thing which vitiates Pitta Dosha such as excessive and continous use of hot, sour, alkaline and indigestion, expose to very intense heat of sun and fire, exertion, anager and irregular diet can cause Pittaj Prameha.
3.   Vataj Prameha Nidan
Excessive and frequent use of astringent pungent bitter ras daily, contact with rough and cold, excessive sexual intercourse and physical vitiates vata.
Types of Prameha according to classics



Doshik type
Charaka
Sushruta
Vagbhat
Madhavakar
Kaphaj Prameha
1
Udakameha
Udakameha
Udakameha
Udakameha
2
Ikshuvalikarasa
Ikshuvalikarasameha
Ikshumeha
Ikshumeha
3
Sandrameha
Sandrameha
Sandrameha
Sandrameha
4
Sandra Prasad
Surameha
Surameha
Surameha
5
Shuklameha
Pistameha
Pistameha
Pistameha
6
Shuklameha
Shuklameha
Shuklameha
Shuklameha
7
Sitameha
-
Sitameha
Sitameha
8
Siktameha
Siktameha
Siktameha
Siktameha
9
Sanayameha
Sanayameha
Sanayameha
Sanayameha
10
Alalmeha
-
Lalameha
Lalameha
11
-
Lavanmeha
-
-
12
-
Phenameha
-
-

Pittaja Prameha
1
Kshara meha
Kshara meha
Kshara meha
Kshara meha
2
Kalameha
-
Kalameha
Kalameha
3
Nilameha
Nilameha
Nilameha
Nilameha
4
Lohitameha
Shonitameha
Raktameha
Raktameha
5
Manjisthameha
Manjisthameha
Manjisthameha
Manjisthameha
6
Haridrameha
Haridrameha
Haridrameha
Haridrameha
7
-
Amalameha
-
-

Vataj Prameha
1
Vasameha
Vasameha
Vasameha
Vasameha
2
Majjameha
Sarpimeha
Majjameha
Majjameha
3
Hastimeha
Hastimeha
Hastimeha
Hastimeha
4
Madhumeha
Ksaudrameha
Madhumeha
Madhumeha

PRAMEHA UPADRAVAS
Kaphaj
Pittaj
Vataj
Makshika Sarpana
Vrushana Avadaran
Hritgraha
Alasya
Basti bheda
Lauloyam
Mamsopachaya
Hrudaya Shool
Anidra
Pratishayaya
Amlika
Stambha
Shaithliya
Paridhupan
Kampa
Arochaka
Sarvanga daha
Shool
Avipaka
Pipasa
Baddha Purishata
Kapha Praseka
Nidranasha
-
Chhardi
Pandu
-
Nidra
Peeta-vena mutra netrata
-
Kasa Swasa
-
-



                          


                              SAMPRAPTI OF PRAMEHA
                                  Hetu Sevan
                                 Tridosh dushti
                              Dhatwagnimandya
             Dhatu Pramantah Vriddhi, Upchaytah Hani
                               Dhatushaithilya  
                            Dhatu Abaddhatwa 
                Meda,Asruk,Shukra,Vasa,Lasika,Majja,Ras,Mans
                               & Oja get vitiated.
                                   Kledanirmiti
       Dehasanchar of vitiated doshas due to looseness of  Dhatu
                    Mix with kleda, vitiated Meda etc. 
                  Convertion of Drava dhatu into urine  
              Dhatuksharan through Mootravaha Srotas
                   Prameha                            Dhatukshay
                                                       Oja gets hampered
                                                          Madhumeha     



Samprapti of Diabetic retinopathy:-
 Bahudravashleshma Nirmiti is the main pathological event in the generation of Prameha. This Kapha, which is increased by Drava property,leads to laxity in Meda and Mans Dhatu predominantly Meda. According to Vagbhatacharya, Siras are generated from the Meda along with its Sneha during the Formation of Meda.Therefore the vitiation of Meda results into Sira dushti (Sira Abaddhata).This leads to loss of permeability and fragility of Siras and results into venous beading and leaking.As the disease progresses, it leads to vitiation of Pitta along kapha and Vata.The retinal vasculature becomes more fragile with increased permeability of vessels due to vitiation of Pitta along with its Ushna and thikshna property.Leaking of RasRaktagat Sneh and Rakta takes place because of this vitiated pitta. described in conventional system of medicine Finally,this pathogenesis goes deeper causing the vitiation of Vata along with Kapha and Pitta.Vitiated Vata along with Rooksha Gun result into loss of elasticity of retinal vessels leading to the formation of Microaneurysms.Also Exudates and Hemorrhages from due to involvement of more number of siras and more bleeding. As the disease progresses further, these exudates and hemorrhages surrounds macula causing macular edema.Rooksha Gun of Vata may be responsible for the formation of new, delicate and brittle vessles i.e. Neovascularization.When the etiological factor vitiates Pitta more,it results into intra-vitreous and IntraRetinal hamorrhages.
                        
 

      SAMPRAPTI OF DIABETIC RETINOPATHY

 Prameha
                            Nidan Sevan
                                      
Kapha(Drava Guna)       Pitta(Ushna Guna)      Vata(Rooksha Guna)
                                Sthan Dushti(Chakshu)
            Meda Dhatu Dushti(Tritiya and Chaturtha Patal)
        Sthanik Sira Vikruti (Sira Abaddhta due to Kapha and Meda)
Vata+Kapha+Meda   Vata+pitta+kapha+Meda  vata+ Pitta+Kapha+Meda  
Sirabhitti karshan          Sirabhitti Bhed                 Navsira nirman     (Thining of Vessles)   (Retinal haemorrhage)       (Formation of New vessles)                                                                                              
Siragat Vyasnirmiti     RasRaktagat Sneh sravan                      
 (Anuerysm)                        (Exudates)     
                 
                                    
 Non-Proliferative Diabetic Retinopathy       Proliferative Diabetic Retinopathy





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