v Tvaca and Dosha :
Tvaca is
one of the site of vata and pitta. (A.WØû.zÉÉ.12/13)
Ø Vata -
Skin has been considered as sparshanemdriya adhishthana
which is function of vata.
(cÉ.xÉÔ.8/10)
Ø Pitta -
bhrajaka
pitta
is located on the tvaca for giving luster and colour.
(cÉ.xÉÔ.12/12)
Ø Kapha - snigdhata, shlakshnata, mruduta, sthirata, shitata,
prasannata, snigdhavarnata
are the attributed to kapha. For ropana karma (self
healing process) kapha is responsible factor.
v Tvaca and Dhatu:
1.rasa -In
the context of tvaka sara purusha lakshna it has been also said as rasa sara.
A 1st layer of tvaca udakadhara also contains rasa (lymph)
so it can be easily understood that there is a relation between tvaca and
rasa.
2.rakta -Among
its functions varna
prasadana- mansa pushti have
been mentioned. (xÉÑ.xÉÔ.15/6)
3.mansa - Twak
is upadhatu of mansa.
(cÉ.xÉÔ.15/7)
4.meda-
Among its functions snehadharana, svedadharana, drutatva has
been mentioned.
5.asthi-
kesha, roma, and nails are mala of asthi dhatu which are embedded in the skin.
6)majja-
Among its functions to from tvakaasneha,
akthisneha.
7)shukra- It
present all over in the body it gives prasannavarnatata
skin and help inregeneration of skin.
v tvaca and mala:
1) sveda:
It is mala of meda which
is excreted by tvaca .
sveda maintain the luster and humidity of skin. (cÉ.xÉÑ.15/5)
2)
Nails and Hairs: These are mala of asthi dhatu and tvakaagata sneha is mala of majja dhatu.
MODERN
REVIEW
The
skin is the first line of defense against the envioronmental agent and mirror
or internal pathology.
v Embryological Description :
The
skin is developed from the surface ectoderm and its underlying mesenchyme (Mesodermal
cells).
1) Surface
ectoderm gives rise to the kertinizing general surface epidermis and its
appendages, the pilosebaceous units, sudariferous glands and nail units at
about 8-10 weeks of gestation.
2) Malacocites,
nerves and specialized sensory receptors arise from the neuroectoderm.
3) Dermis
and its other elements in the skin that is langerhans cells, macrophages, mass
cell, fibroblasts etc originate from the mesoderm.
v Macroscopic
structures :
The
skin is the organ of integumentory system that is covering system of the
body. It is formed by about-
v 8%
of the total body mass.
v 2.2
square meter covering area.
v 16%
of total body weight.
v Thickness
of the skin is different according to maturation, aging and regional
specialization. It may be 0.5 mm on the
eyelid and 4 mm on heal.
Most of the body skin is average 1-2cm thick. Skin is a fascinating
orgain as it forms a self renewing and self repairing interface between the
body and its
v environment.
v Within
limit, it forms an effective barrier against microbial invasion and has
properties which can protect against mechanical, chemical, cosmetic, thermal
and phototic damage.
v Microscopic Structure :
It
is characterized by the epidermis, dermis and adenaxa.
1) Epidermis:
It
is a compound tissue consisting mainly of the continuously self replacing
keratinized stratified squamous epithelium.
It varies in thickness 0.04 mm on the eyelid and 0.16 mm on palms, 0.1
mm is average thickness. Epidermis
contains five layers (Strata).
1) Stratum bascal 2) Stratum
spinosum
3)
Stratum granulosum 4) Stratum
corneum
5) Stratum lucidum
1) Stratum Bascal:
It
is deepest layer of the epidermis and formed by a single row of columnar
kerationcytes. Four types of cells are
germinated through these layers which are keratinocytes, melanocytes,
langerhans cells and merkels cells.
2) Stratum spinosum:
It
lies super ficial to bascal and it consists of 5 to 12 layers of polyhedral
keratinocytes cells are joined tightly to other cells by bundles of
intermediate filaments of the cytoskeleton.This arrangement provides both
strength and flexibility.
3) Stratum granulosum:
It
is 3 to 5 layers of flattened kerationocytes that contains darkly staining
granules of proteins called karatophylin.
The lipid rich secretion produced by the lamellar granules work as a
water repellent sealant that retards loss of body fluid and entry of foreign
materials.
4) Stratum lucidum:
It
is present only in the skin of fingertips, palms and soles. It consists of 3-5
layers of clear, flat, dead kerationocytes.
5) Stratum corneum:
This
is the most superficial layer consisting of anucleated flattened confirmed
25-30 layers of dead karatinocytes. These cells are continuously shed and
replaced by cells from the deeper strata.
It serves as an effective water repellant barrier and also protects
against injury and microbes.
Adnexa
of epidermis:
It
contains the eccrine glands, apocrine glands and the pilosebaceous apparatus.
1)
Eccrine glands:
These are distributed all over body except the venillion borders of the
lips nailbeds, labia minora, glans penis etc.There density is maximum on the
palms, sales and axillae.These glands initiate the sweat formation which
dissipate heat by evaporation.
2)
Apocrine glands:
These are located in the axillar,
areolae, periumbilical, perianal, external ear etc areas. These are small and
nonfunctional till puberty, after which they enlarge.
3)
Hair follicles:
They presents all over body except
sime parts like palm, sole etc and they protects scalp from injury and sunrays
and decrease heat loss.
4)
Sebaceous gland:
They are lipid producing structures disturbed all over body except palms
and soles.
5)
Nail unit:
The nail unit helps in the appreciation of the fine and tactile
stimulation, protect the terminal phalanges from trauma.
Dermis
:
The dermis rests upon the subcutaneous fat and is 15-40 time thicker
than the epidermis. The dermis is composed mainly of noncellular connective
tissue containing collagen, elastic tissue and ground substances within which
are embedded the nerves, blood vessels, lymphatics, muscles, and pilosebaceous
apocrine and eccrine sweat unit. Dermis can be divided into
1)
Superficial
- Papillary region
2)
Deeper
- Reticular region
1.
Superficial – Papillary region
It consists of
areolar connective tissue containing fine elastic fibers. Elastic fibers play a
role in maintaining the elasticity of the skin
2.
Deeper – Reticular region
It consists of dense irregular
connective tissue containing bundle of collagen and some elastic fibers. Both
these provides strength elasticity to skin.
Pigmentation of skin
Melanin, carotene and haemoglobin- these three pigmemts give skin a wide
variety of colour. Melanin located in epidermis, carotene is mostly in the
stratum corneum and dermis and haemoglobin is in red blood cells within
capillaries in the dermis.
PHYSIOLOGY OF SKIN:
- Thermoregulation
- Protection
- Cutaneous
Sensation
- Excretion and
absorption
- Synthesis of
vitaminD
- Immunity
- Blood reservoir
- Socio sexual
communication
- Individual
identification
|
Sr
No.
|
Ancient
term
|
Modern
term
|
Parts
of skin
|
|
1.
|
Avabhasini
|
Stratum corneum
|
Epidermis
|
|
2.
|
Lohita
|
Stratum lucidum
|
Epidermis
|
|
3.
|
Shweta
|
Stratum granulosum
|
Epidermis
|
|
4.
|
Tamra
|
Malpighian layer
|
Epidermis
|
|
5.
|
Vedini
|
Papillary layer
|
Dermis
|
|
6.
|
Rohini
|
Reticular layer
|
Dermis
|
|
7.
|
Mansadhara
|
Subcutaneous tissue Muscular layer
|
Dermis
|